共同研究により得られた成果

  1. Guan M, Bogani D, Marschall S, Raspa M, Takeo T, Nakagata N, Taft R, Fray M. Contemporary techniques for freezing mouse spermatozoa. Curr Protoc Mouse Biol. 2014 Sep 3;4(3):85-104.
    http://www.ncbi.nlm.nih.gov/pubmed/25723962

  2. Guan M, Bogani D, Marschall S, Raspa M, Takeo T, Nakagata N, Fray M. In Vitro Fertilization in Mice Using the MBCD-GSH Protocol. Curr Protoc Mouse Biol. 2014 Jun 16;4(2):67-83.
    http://www.ncbi.nlm.nih.gov/pubmed/25723919

  3. Kenyon J, Guan M, Bogani D, Marschall S, Raspa M, Pickard A, Takeo T, Nakagata N, Fray M. Transporting mouse embryos and germplasm as frozen or unfrozen materials. Curr Protoc Mouse Biol. 2014 Jun 16;4(2):47-65.
    http://www.ncbi.nlm.nih.gov/pubmed/25723918

  4. Guan M, Bogani D, Marschall S, Raspa M, Takeo T, Nakagata N, Fray M. Conservation of mouse models through embryo freezing. Curr Protoc Mouse Biol. 2014 Dec 11;4(4):205-27.
    http://www.ncbi.nlm.nih.gov/pubmed/25723186

  5. Maeda Y, Motoyama K, Higashi T, Horikoshi Y, Takeo T, Nakagata N, Kurauchi Y, Katsuki H, Ishitsuka Y, Kondo Y, Irie T, Furuya H, Era T, Arima H. Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients. J Pharm Pharmacol. 2015 Apr 7.
    http://www.ncbi.nlm.nih.gov/pubmed/25851126

  6. Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G. Tissue-specific roles of FGF signaling in external genitalia development. Dev Dyn. 2015 Mar 26.
    http://www.ncbi.nlm.nih.gov/pubmed/25820239

  7. Okazawa M, Murashima A, Harada M, Nakagata N, Noguchi M, Morimoto M, Kimura T, Ornitz DM, Yamada G. Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development. Dev Biol. 2015 Apr 1;400(1):139-47.
    http://www.ncbi.nlm.nih.gov/pubmed/25678108

  8. Soga M, Ishitsuka Y, Hamasaki M, Yoneda K, Furuya H, Matsuo M, Ihn H, Fusaki N, Nakamura K, Nakagata N, Endo F, Irie T, Era T. HPGCD Outperforms HPBCD as a Potential Treatment for Niemann-Pick Disease Type C During Disease Modeling with iPS Cells. Stem Cells. 2015 Apr;33(4):1075-88.
    http://www.ncbi.nlm.nih.gov/pubmed/25522247

  9. Takamatsu K, Ikeda T, Haruta M, Matsumura K, Ogi Y, Nakagata N, Uchino M, Ando Y, Nishimura Y, Senju S. Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2. Stem Cell Res. 2014 Nov;13(3 Pt A):442-53.
    http://www.ncbi.nlm.nih.gov/pubmed/25460605

  10. Suzuki K, Numata T, Suzuki H, Raga DD, Ipulan LA, Yokoyama C, Matsushita S, Hamada M, Nakagata N, Nishinakamura R, Kume S, Takahashi S, Yamada G. Sexually dimorphic expression of Mafb regulates masculinization of the embryonic urethral formation. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16407-12.
    http://www.ncbi.nlm.nih.gov/pubmed/25362053

  11. Ipulan LA, Suzuki K, Sakamoto Y, Murashima A, Imai Y, Omori A, Nakagata N, Nishinakamura R, Valasek P, Yamada G. Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle. Endocrinology. 2014 Jul;155(7):2467-79.
    http://www.ncbi.nlm.nih.gov/pubmed/24742196

  12. Omori A, Miyagawa S, Ogino Y, Harada M, Ishii K, Sugimura Y, Ogino H, Nakagata N, Yamada G. Essential roles of epithelial bone morphogenetic protein signaling during prostatic development. Endocrinology. 2014 Jul;155(7):2534-44.
    http://www.ncbi.nlm.nih.gov/pubmed/24731097

  13. Miyagawa S, Harada M, Matsumaru D, Tanaka K, Inoue C, Nakahara C, Haraguchi R, Matsushita S, Suzuki K, Nakagata N, Ng RC, Akita K, Lui VC, Yamada G. Disruption of the temporally regulated cloaca endodermal ホイ-catenin signaling causes anorectal malformations. Cell Death Differ. 2014 Jun;21(6):990-7.
    http://www.ncbi.nlm.nih.gov/pubmed/24632946

  14. Araki M, Nakahara M, Muta M, Itou M, Yanai C, Yamazoe F, Miyake M, Morita A, Araki M, Okamoto Y, Nakagata N, Yoshinobu K, Yamamura K, Araki K. Database for exchangeable gene trap clones: pathway and gene ontology analysis of exchangeable gene trap clone mouse lines. Dev Growth Differ. 2014 Feb;56(2):161-74.
    http://www.ncbi.nlm.nih.gov/pubmed/24444128

  15. Murashima A, Akita H, Okazawa M, Kishigami S, Nakagata N, Nishinakamura R, Yamada G. Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm. Dev Biol. 2014 Feb 1;386(1):216-26.
    http://www.ncbi.nlm.nih.gov/pubmed/24370450

  16. Sakano D, Shiraki N, Kikawa K, Yamazoe T, Kataoka M, Umeda K, Araki K, Mao D, Matsumoto S, Nakagata N, Andersson O, Stainier D, Endo F, Kume K, Uesugi M, Kume S. VMAT2 identified as a regulator of late-stage β-cell differentiation. Nat Chem Biol. 2014 Feb;10(2):141-8.
    http://www.ncbi.nlm.nih.gov/pubmed/24316738

  17. Matsumaru D, Haraguchi R, Moon AM, Satoh Y, Nakagata N, Yamamura K, Takahashi N, Kitazawa S, Yamada G. Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation. Eur J Hum Genet. 2014 Mar;22(3):350-7.
    http://www.ncbi.nlm.nih.gov/pubmed/23942202

  18. Nakahara M, Tateyama H, Araki M, Nakagata N, Yamamura K, Araki K. Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39.
    http://www.ncbi.nlm.nih.gov/pubmed/23604909

  19. Mazahery AR, Suzuki K, Nagafuchi A, Miyajima M, Nakagata N, Orvis GD,Behringer RR, Yamada G. Functional analysis of ectodermal ホイ-catenin during external genitalia formation. Congenit Anom (Kyoto). 2013 Mar;53(1):34-41.
    http://www.ncbi.nlm.nih.gov/pubmed/23480356

  20. Semba K, Araki K, Matsumoto K, Suda H, Ando T, Sei A, Mizuta H, Takagi K, Nakahara M, Muta M, Yamada G, Nakagata N, Iida A, Ikegawa S, Nakamura Y, Araki M, Abe K, Yamamura K. Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice. PLoS Genet. 2013;9(2):e1003204.
    http://www.ncbi.nlm.nih.gov/pubmed/23436999

  21. Hojo H, Ohba S, Taniguchi K, Shirai M, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Mishina Y, Yamada M, Konno T, Takato T, Kawaguchi H, Kambara H, Chung UI. Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in
    the perichondrium. J Biol Chem. 2013 Apr 5;288(14):9924-32.
    http://www.ncbi.nlm.nih.gov/pubmed/23423383

  22. Suzuki K, Adachi Y, Numata T, Nakada S, Yanagita M, Nakagata N, Evans SM, Graf D, Economides A, Haraguchi R, Moon AM, Yamada G. Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia. PLoS One. 2012;7(9):e43453.
    http://www.ncbi.nlm.nih.gov/pubmed/23028455

  23. Villacorte M, Suzuki K, Hirasawa A, Ohkawa Y, Suyama M, Maruyama T, Aoki D, Ogino Y, Miyagawa S, Terabayashi T, Tomooka Y, Nakagata N, Yamada G. β-Catenin signaling regulates Foxa2 expression during endometrial hyperplasia formation.
    Oncogene. 2013 Jul 18;32(29):3477-82.
    http://www.ncbi.nlm.nih.gov/pubmed/22945641

  24. Haraguchi R, Matsumaru D, Nakagata N, Miyagawa S, Suzuki K, Kitazawa S, Yamada G. The hedgehog signal induced modulation of bone morphogenetic protein signaling: an essential signaling relay for urinary tract morphogenesis. PLoS One. 2012;7(7):e42245.
    http://www.ncbi.nlm.nih.gov/pubmed/22860096

  25. Hayashi H, Eguchi Y, Fukuchi-Nakaishi Y, Takeya M, Nakagata N, Tanaka K, Vance JE, Tanihara H. A potential neuroprotective role of apolipoprotein E-containing lipoproteins through low density lipoprotein receptor-related protein 1 in normal tension glaucoma. J Biol Chem. 2012 Jul 20;287(30):25395-406.
    http://www.ncbi.nlm.nih.gov/pubmed/22674573

  26. Hojo H, Ohba S, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, Chung UI. Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification. J Biol Chem. 2012 May 18;287(21):17860-9.
    http://www.ncbi.nlm.nih.gov/pubmed/22493482

  27. Araki S, Izumiya Y, Hanatani S, Rokutanda T, Usuku H, Akasaki Y, Takeo T, Nakagata N, Walsh K, Ogawa H. Akt1-mediated skeletal muscle growth attenuates cardiac dysfunction and remodeling after experimental myocardial infarction. Circ Heart Fail. 2012 Jan;5(1):116-25.
    http://www.ncbi.nlm.nih.gov/pubmed/22135402

  28. Liu L, Suzuki K, Nakagata N, Mihara K, Matsumaru D, Ogino Y, Yashiro K, Hamada H, Liu Z, Evans SM, Mendelsohn C, Yamada G. Retinoic acid signaling regulates sonic hedgehog and bone morphogenetic protein signalings during genital tubercle development. Birth Defects Res B Dev Reprod Toxicol. 2012 Feb;95(1):79-88.
    http://www.ncbi.nlm.nih.gov/pubmed/22127979

  29. Kawakami M, Umeda M, Nakagata N, Takeo T, Yamamura K. Novel migrating mouse neural crest cell assay system utilizing P0-Cre/EGFP fluorescent time-lapse imaging. BMC Dev Biol. 2011 Nov 9;11:68.
    http://www.ncbi.nlm.nih.gov/pubmed/22070366

  30. Omori A, Harada M, Ohta S, Villacorte M, Sugimura Y, Shiraishi T, Suzuki K, Nakagata N, Ito T, Yamada G. Epithelial Bmp (Bone morphogenetic protein) signaling for bulbourethral gland development: a mouse model for congenital cystic dilation. Congenit Anom (Kyoto). 2011 Sep;51(3):102-9.
    http://www.ncbi.nlm.nih.gov/pubmed/21848994

  31. Miyagawa S, Matsumaru D, Murashima A, Omori A, Satoh Y, Haraguchi R, Motoyama J, Iguchi T, Nakagata N, Hui CC, Yamada G. The role of sonic hedgehog-Gli2 pathway in the masculinization of external genitalia. Endocrinology. 2011 Jul;152(7):2894-903.
    http://www.ncbi.nlm.nih.gov/pubmed/21586556

  32. Kawakami M, Yoshimoto T, Nakagata N, Yamamura K, Siesjo BK. Effects of cyclosporin A administration on gene expression in rat brain. Brain Inj. 2011;25(6):614-23.
    http://www.ncbi.nlm.nih.gov/pubmed/21534739

  33. Matsumaru D, Haraguchi R, Miyagawa S, Motoyama J, Nakagata N, Meijlink F, Yamada G. Genetic analysis of Hedgehog signaling in ventral body wall development and the onset of omphalocele formation. PLoS One. 2011 Jan 20;6(1):e16260.
    http://www.ncbi.nlm.nih.gov/pubmed/21283718

  34. Ando T, Semba K, Suda H, Sei A, Mizuta H, Araki M, Abe K, Imai K, Nakagata N, Araki K, Yamamura K. The floor plate is sufficient for development of the sclerotome and spine without the notochord. Mech Dev. 2011 Jan-Feb;128(1-2):129-40.
    http://www.ncbi.nlm.nih.gov/pubmed/21111815

  35. Sato Y, Takata H, Kobayashi N, Nagata S, Nakagata N, Ueno T, Takiguchi M. Failure of effector function of human CD8+ T Cells in NOD/SCID/JAK3-/- immunodeficient mice transplanted with human CD34+ hematopoietic stem cells. PLoS One. 2010 Oct 1;5(10). pii: e13109.
    http://www.ncbi.nlm.nih.gov/pubmed/20957041

  36. Namba T, Hoshino T, Suemasu S, Takarada-Iemata M, Hori O, Nakagata N, Yanaka A, Mizushima T. Suppression of expression of endoplasmic reticulum chaperones by Helicobacter pylori and its role in exacerbation of non-steroidal anti-inflammatory drug-induced gastric lesions. J Biol Chem. 2010 Nov
    26;285(48):37302-13.
    http://www.ncbi.nlm.nih.gov/pubmed/20861013

  37. Ramadan A, Nobuhisa I, Yamasaki S, Nakagata N, Taga T. Cells with hematopoietic activity in the mouse placenta reside in side population. Genes Cells. 2010 Sep 1;15(9):983-94.
    http://www.ncbi.nlm.nih.gov/pubmed/20718937

  38. Uchiyama Y, Sakaguchi M, Terabayashi T, Inenaga T, Inoue S, Kobayashi C, Oshima N, Kiyonari H, Nakagata N, Sato Y, Sekiguchi K, Miki H, Araki E, Fujimura S, Tanaka SS, Nishinakamura R. Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9240-5.
    http://www.ncbi.nlm.nih.gov/pubmed/20439720

  39. Wang J, Ohmuraya M, Suyama K, Hirota M, Ozaki N, Baba H, Nakagata N, Araki K, Yamamura K. Relationship of strain-dependent susceptibility to experimentally induced acute pancreatitis with regulation of Prss1 and Spink3 expression. Lab Invest. 2010 May;90(5):654-64.
    http://www.ncbi.nlm.nih.gov/pubmed/20157294

  40. Villacorte M, Suzuki K, Hayashi K, de Sousa Lopes SC, Haraguchi R, Taketo MM, Nakagata N, Yamada G. Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation. Biochem Biophys Res Commun. 2010 Jan 22;391(4):1653-7.
    http://www.ncbi.nlm.nih.gov/pubmed/20043884

  41. Tabata M, Kadomatsu T, Fukuhara S, Miyata K, Ito Y, Endo M, Urano T, Zhu HJ, Tsukano H, Tazume H, Kaikita K, Miyashita K, Iwawaki T, Shimabukuro M, Sakaguchi K, Ito T, Nakagata N, Yamada T, Katagiri H, Kasuga M, Ando Y, Ogawa H, Mochizuki N, Itoh H, Suda T, Oike Y. Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. Cell Metab.
    2009 Sep;10(3):178-88.
    http://www.ncbi.nlm.nih.gov/pubmed/19723494

  42. Nitta Y, Shigeyoshi Y, Nakagata N, Kaneko T, Nitta K, Harada T, Ishizaki F, Townsend J. Kinetics of blood glucose in mice carrying hemizygous Pax6. Exp Anim. 2009 Apr;58(2):105-12.
    http://www.ncbi.nlm.nih.gov/pubmed/19448333

  43. Miyagawa S, Satoh Y, Haraguchi R, Suzuki K, Iguchi T, Taketo MM, Nakagata N, Matsumoto T, Takeyama K, Kato S, Yamada G. Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia. Mol Endocrinol. 2009 Jun;23(6):871-80.
    http://www.ncbi.nlm.nih.gov/pubmed/19282366

  44. Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G. Embryonic hair follicle fate change by augmented beta-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72.
    http://www.ncbi.nlm.nih.gov/pubmed/19141668

  45. Araki K, Takeda N, Yoshiki A, Obata Y, Nakagata N, Shiroishi T, Moriwaki K, Yamamura K. Establishment of germline-competent embryonic stem cell lines from the MSM/Ms strain. Mamm Genome. 2009 Jan;20(1):14-20.
    http://www.ncbi.nlm.nih.gov/pubmed/19082856

  46. Zhang D, Shimizu T, Araki N, Hirota T, Yoshie M, Ogawa K, Nakagata N, Takeya M, Saya H. Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice. Oncogene. 2008 Jul 17;27(31):4305-14.
    http://www.ncbi.nlm.nih.gov/pubmed/18372918

  47. Nishida H, Miyagawa S, Vieux-Rochas M, Morini M, Ogino Y, Suzuki K, Nakagata N, Choi HS, Levi G, Yamada G. Positive regulation of steroidogenic acute regulatory protein gene expression through the interaction between Dlx and GATA-4 for testicular steroidogenesis. Endocrinology. 2008 May;149(5):2090-7.
    http://www.ncbi.nlm.nih.gov/pubmed/18276760

  48. Yoshida M, Kuwahara K, Shimasaki T, Nakagata N, Matsuoka M, Sakaguchi N. GANP suppresses DNA recombination, measured by direct-repeat beta-galactosidase gene construct, but does not suppress the type of recombination applying to immunoglobulin genes in mammalian cells. Genes Cells. 2007 Oct;12(10):1205-13.
    http://www.ncbi.nlm.nih.gov/pubmed/17903179

  49. Yokomine K, Nakatsura T, Senju S, Nakagata N, Minohara M, Kira J, Motomura Y, Kubo T, Sasaki Y, Nishimura Y. Regression of intestinal adenomas by vaccination with heat shock protein 105-pulsed bone marrow-derived dendritic cells in Apc(Min/+) mice. Cancer Sci. 2007 Dec;98(12):1930-5.
    http://www.ncbi.nlm.nih.gov/pubmed/17892515

  50. Suzuki K, Haraguchi R, Ogata T, Barbieri O, Alegria O, Vieux-Rochas M, Nakagata N, Ito M, Mills AA, Kurita T, Levi G, Yamada G. Abnormal urethra formation in mouse models of split-hand/split-foot malformation type 1 and type 4. Eur J Hum Genet. 2008 Jan;16(1):36-44.
    http://www.ncbi.nlm.nih.gov/pubmed/17878916

  51. Nitta Y, Yoshida K, Nakagata N, Nitta K, Harada T, Ishizaki F. Intestinal tumorigenicity of mice carrying hemizygous Pax6, Pax6(Sey-4H). Exp Anim. 2007 Jul;56(4):289-94.
    http://www.ncbi.nlm.nih.gov/pubmed/17660683

  52. Nobuhisa I, Ohtsu N, Okada S, Nakagata N, Taga T. Identification of a population of cells with hematopoietic stem cell properties in mouse aorta-gonad-mesonephros cultures. Exp Cell Res. 2007 Mar 10;313(5):965-74.
    http://www.ncbi.nlm.nih.gov/pubmed/17275811

  53. Yamaguchi Y, Nagase T, Tomita T, Nakamura K, Fukuhara S, Amano T, Yamamoto H, Ide Y, Suzuki M, Teramoto S, Asano T, Kangawa K, Nakagata N, Ouchi Y, Kurihara H. Beta-defensin overexpression induces progressive muscle degeneration in mice. Am J Physiol Cell Physiol. 2007 Jun;292(6):C2141-9.
    http://www.ncbi.nlm.nih.gov/pubmed/17215327

  54. Haraguchi R, Motoyama J, Sasaki H, Satoh Y, Miyagawa S, Nakagata N, Moon A, Yamada G. Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling. Development. 2007 Feb;134(3):525-33.
    http://www.ncbi.nlm.nih.gov/pubmed/17202190

  55. Hoshii T, Takeo T, Nakagata N, Takeya M, Araki K, Yamamura K. LGR4 regulates the postnatal development and integrity of male reproductive tracts in mice. Biol Reprod. 2007 Feb;76(2):303-13.
    http://www.ncbi.nlm.nih.gov/pubmed/17079737

  56. Yamada G, Suzuki K, Haraguchi R, Miyagawa S, Satoh Y, Kamimura M, Nakagata N, Kataoka H, Kuroiwa A, Chen Y. Molecular genetic cascades for external genitalia formation: an emerging organogenesis program. Dev Dyn. 2006 Jul;235(7):1738-52. Review.
    http://www.ncbi.nlm.nih.gov/pubmed/16598715

  57. Miura K, Yoshinobu K, Imaizumi T, Haruna K, Miyamoto Y, Yoneda Y, Nakagata N, Araki M, Miyakawa T, Yamamura K, Araki K. Impaired expression of importin/karyopherin beta1 leads to post-implantation lethality. Biochem Biophys Res Commun. 2006 Mar 3;341(1):132-8.
    http://www.ncbi.nlm.nih.gov/pubmed/16414015

  58. Semba K, Araki K, Li Z, Matsumoto K, Suzuki M, Nakagata N, Takagi K, Takeya M, Yoshinobu K, Araki M, Imai K, Abe K, Yamamura K. A novel murine gene, Sickle tail, linked to the Danforth's short tail locus, is required for normal development of the intervertebral disc. Genetics. 2006 Jan;172(1):445-56.
    http://www.ncbi.nlm.nih.gov/pubmed/16204209

  59. Taniwaki T, Haruna K, Nakamura H, Sekimoto T, Oike Y, Imaizumi T, Saito F, Muta M, Soejima Y, Utoh A, Nakagata N, Araki M, Yamamura K, Araki K. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Dev Growth Differ. 2005 Apr;47(3):163-72.
    http://www.ncbi.nlm.nih.gov/pubmed/15840001

  60. Oike Y, Akao M, Yasunaga K, Yamauchi T, Morisada T, Ito Y, Urano T, Kimura Y, Kubota Y, Maekawa H, Miyamoto T, Miyata K, Matsumoto S, Sakai J, Nakagata N, Takeya M, Koseki H, Ogawa Y, Kadowaki T, Suda T. Angiopoietin-related growth factor antagonizes obesity and insulin resistance. Nat Med. 2005 Apr;11(4):400-8.
    http://www.ncbi.nlm.nih.gov/pubmed/15778720

  61. Kanato K, Hosen N, Yanagihara M, Nakagata N, Shirakata T, Nakazawa T, Nishida S, Tsuboi A, Kawakami M, Masuda T, Oka Y, Oji Y, Ijpenberg A, Hastie ND, Sugiyama H. The Wilms' tumor gene WT1 is a common marker of progenitor cells in fetal liver. Biochem Biophys Res Commun. 2005 Jan 28;326(4):836-43.
    http://www.ncbi.nlm.nih.gov/pubmed/15607745

  62. Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Hamaguchi I, Nomiyama K, Hosokawa K, Sakurada K, Nakagata N, Ikeda Y, Mak TW, Suda T. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature. 2004 Oct 21;431(7011):997-1002.
    http://www.ncbi.nlm.nih.gov/pubmed/15496926

  63. Nitta Y, Yoshida K, Satoh K, Senba K, Nakagata N, Peters J, Cattanach BM. Spontaneous and radiation-induced leukemogenesis of the mouse small eye mutant, Pax6(Sey3H). J Radiat Res. 2004 Jun;45(2):245-51.
    http://www.ncbi.nlm.nih.gov/pubmed/15304967

  64. Mitsunaga K, Araki K, Mizusaki H, Morohashi K, Haruna K, Nakagata N, Giguティre
    V, Yamamura K, Abe K. Loss of PGC-specific expression of the orphan nuclear receptor ERR-beta results in reduction of germ cell number in mouse embryos. Mech Dev. 2004 Mar;121(3):237-46.
    http://www.ncbi.nlm.nih.gov/pubmed/15003627

  65. Kuwahara K, Fujimura S, Takahashi Y, Nakagata N, Takemori T, Aizawa S, Sakaguchi N. Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1010-5. Epub 2004 Jan 8.
    http://www.ncbi.nlm.nih.gov/pubmed/14715907

  66. Kamimura E, Nakashima T, Ogawa M, Ohwada K, Nakagata N. Study of low-temperature (4 degrees C) transport of mouse two-cell embryos enclosed in oviducts. Comp Med. 2003 Aug;53(4):393-6.
    http://www.ncbi.nlm.nih.gov/pubmed/14524415

  67. Suzuki K, Satoh Y, Lei L, Ohta S, Urano T, Nakagata N, Yamada G. Developmental biology meets with reproductive engineering; interdisciplinary science area as a breakthrough. Cell Mol Biol (Noisy-le-grand). 2003 Jun;49(4):653-60. Review.
    http://www.ncbi.nlm.nih.gov/pubmed/12899459

  68. Oike Y, Yasunaga K, Ito Y, Matsumoto S, Maekawa H, Morisada T, Arai F, Nakagata N, Takeya M, Masuho Y, Suda T. Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9494-9. Epub 2003 Jul 18.
    http://www.ncbi.nlm.nih.gov/pubmed/12871997

  69. Kyuwa S, Nishikawa T, Kaneko T, Nakashima T, Kawano K, Nakamura N, Noguchi K, Urano T, Itoh T, Nakagata N. Experimental evaluation of cross-contamination between cryotubes containing mouse 2-cell embryos and murine pathogens in liquid nitrogen tanks. Exp Anim. 2003 Jan;52(1):67-70.
    http://www.ncbi.nlm.nih.gov/pubmed/12638239

  70. Noguchi H, Kaname T, Sekimoto T, Senba K, Nagata Y, Araki M, Abe M, Nakagata N, Ono T, Yamamura K, Araki K. Naso-maxillary deformity due to frontonasal expression of human transthyretin gene in transgenic mice. Genes Cells. 2002 Oct;7(10):1087-98.
    http://www.ncbi.nlm.nih.gov/pubmed/12354101

  71. Noguchi H, Ohta M, Wakasugi S, Noguchi K, Nakamura N, Nakamura O, Miyakawa K, Takeya M, Suzuki M, Nakagata N, Urano T, Ono T, Yamamura K. Effect of the intestinal flora on amyloid deposition in a transgenic mouse model of familial amyloidotic polyneuropathy. Exp Anim. 2002 Jul;51(4):309-16.
    http://www.ncbi.nlm.nih.gov/pubmed/12221923

  72. Oike Y, Ito Y, Hamada K, Zhang XQ, Miyata K, Arai F, Inada T, Araki K, Nakagata N, Takeya M, Kisanuki YY, Yanagisawa M, Gale NW, Suda T. Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells. Blood. 2002 Aug 15;100(4):1326-33.
    http://www.ncbi.nlm.nih.gov/pubmed/12149214

  73. Ohtsuka S, Takaki S, Iseki M, Miyoshi K, Nakagata N, Kataoka Y, Yoshida N, Takatsu K, Yoshimura A. SH2-B is required for both male and female reproduction. dMol Cell Biol. 2002 May;22(9):3066-77.
    http://www.ncbi.nlm.nih.gov/pubmed/11940664


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高基準清浄動物

  • 概要
  • データベース
  • 保存
  • 入手
  • 料金
  • 概要
  • 保存
  • 入手
  • 料金
マウスの輸送
遺伝子改変マウスの輸送
微生物学的検査品質管理
実績
R-BASE
FIMRe
  • マウス
  • マウス入手
  • マウス
  • マウス増産
  • マウス
  • マウス清浄化
contribution
研修会
manual
Reproduction
CARD
IRDA
熊本大学

熊本大学
生命資源研究・支援センター
動物資源開発研究施設(CARD)
資源開発分野

〒860-0811
熊本県熊本市中央区本荘2-2-1
TEL  :096-373-6575
FAX  :096-373-6566
Email :card(a)kumamoto-u.ac.jp
窓口担当:岩本
メンバー

お問い合わせ

トップページ 活動について 地図 メンバー 研究活動

マウスバンク 公開マウスバンク 有償マウスバンク 技術と貢献
微生物学的検査 保存 保存 開発・応用・普及
保存系統の品質管理 入手 入手 技術研修会
マウス等の輸送 料金 料金 海外研修会
業務実績 情報公開 応用 共同研究
規則 用語   FIMRe
  遺伝子改変マウスの命名法   科研費「新学術領域研究」
  遺伝子などの命名   NBRP
      ゲノム編集

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